- 产品信息
商品描述
靶点-Target
p40/p63
反应性
Human,Mouse,Rat,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
77kD
MW(Observed)
77kD
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT-P63
免疫原
Synthesized peptide derived from human p63 AA range: 600-680
特异性
The antibody can specifically recognize human p63 protein, including ΔNp63 and TAp63. In western blotting of A431, Hela cell lysates, the antibody can label a 77 kDa band corresponding to p63, while there is no band detected in p63 knock out Hela cell lysate.
基因名称
TP63 KET P63 P73H P73L TP73L
蛋白名称
Tumor protein 63 (p63) (Chronic ulcerative stomatitis protein) (CUSP) (Keratinocyte transcription factor KET) (Transformation-related protein 63) (TP63) (Tumor protein p73-like) (p73L) (p40) (p51)
别名
AIS;Amplified in squamous cell carcinoma;B;p51A;B;p51B;Chronic ulceRative stomatitis protein;CUSP;DN p63 alpha 1;DNp63;EEC3;id:ibd3516;KeRatinocyte transcription factor;KeRatinocyte transcription factor KET;KET;LMS;MGC115972;MGC192897;NBP;OFC8;OTTHUMP00000209732;OTTHUMP00000209733;OTTHUMP00000209734;OTTHUMP00000209735;OTTHUMP00000209737;OTTHUMP00000209738;OTTHUMP00000209739;OTTHUMP00000209740;OTTHUMP00000209741;OTTHUMP00000209742;OTTHUMP00000209743;OTTHUMP00000209744;p40;p51;P51/P63;p53-related protein p63;p53CP;p63;P63_HUMAN;p73H;p73L;RHS;SHFM4;TAp63alpha;TP53CP;TP53L;TP63;TP73L;Transformation related protein 63;Transformation-related protein 63;Trp53rp1;Trp63;Tumor protein 63;Tumor protein p53-competing protein;Tumor protein p53-like;Tumor protein p63;Tumor protein p63 deltaN isoform delta;Tumor protein p73;Tumor protein p73-like
Organism-1
Human
基因ID-1
8626
SwissProt-1
Q9H3D4
背景
P63 is a nuclear protein transcription factor located on chromosome 3q27-29. It is a member of p53 gene family and plays an important role in the growth and development of a variety of epithelial organs. P63 was localized in the basal cells of squamous epithelium and urethral epithelium, myoepithelial cells of breast, sweat gland and salivary gland, basal cells of prostate and basal cells of skin squamous epithelium. P63 is a marker of basal cell carcinoma, squamous cell carcinoma and urinary tract transitional cell carcinoma. It can be used in the study of primary skin tumors, metastatic adenocarcinoma, benign and malignant breast lesions and prostate cancer.
细胞定位
Nuclear





