p63 (ABT-P63) mouse mAb

活动价:

¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2601874

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商品描述
  • 靶点-Target

    p40/p63

  • 反应性

    Human,Mouse,Rat,

  • 应用

    IHC,WB,IF,ELISA

  • 宿主物种-Host Species

    Mouse

  • 同种型-Isotype

    IgG1,Kappa

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    77kD

  • MW(Observed)

    77kD

  • 推荐稀释比

    IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein G

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    ABT-P63

  • 免疫原

    Synthesized peptide derived from human p63 AA range: 600-680

  • 特异性

    The antibody can specifically recognize human p63 protein, including ΔNp63 and TAp63. In western blotting of A431, Hela cell lysates, the antibody can label a 77 kDa band corresponding to p63, while there is no band detected in p63 knock out Hela cell lysate.

  • 基因名称

    TP63 KET P63 P73H P73L TP73L

  • 蛋白名称

    Tumor protein 63 (p63) (Chronic ulcerative stomatitis protein) (CUSP) (Keratinocyte transcription factor KET) (Transformation-related protein 63) (TP63) (Tumor protein p73-like) (p73L) (p40) (p51)

  • 别名

    AIS;Amplified in squamous cell carcinoma;B;p51A;B;p51B;Chronic ulceRative stomatitis protein;CUSP;DN p63 alpha 1;DNp63;EEC3;id:ibd3516;KeRatinocyte transcription factor;KeRatinocyte transcription factor KET;KET;LMS;MGC115972;MGC192897;NBP;OFC8;OTTHUMP00000209732;OTTHUMP00000209733;OTTHUMP00000209734;OTTHUMP00000209735;OTTHUMP00000209737;OTTHUMP00000209738;OTTHUMP00000209739;OTTHUMP00000209740;OTTHUMP00000209741;OTTHUMP00000209742;OTTHUMP00000209743;OTTHUMP00000209744;p40;p51;P51/P63;p53-related protein p63;p53CP;p63;P63_HUMAN;p73H;p73L;RHS;SHFM4;TAp63alpha;TP53CP;TP53L;TP63;TP73L;Transformation related protein 63;Transformation-related protein 63;Trp53rp1;Trp63;Tumor protein 63;Tumor protein p53-competing protein;Tumor protein p53-like;Tumor protein p63;Tumor protein p63 deltaN isoform delta;Tumor protein p73;Tumor protein p73-like

  • Organism-1

    Human

  • 基因ID-1

    8626

  • SwissProt-1

    Q9H3D4

  • 背景

    P63 is a nuclear protein transcription factor located on chromosome 3q27-29. It is a member of p53 gene family and plays an important role in the growth and development of a variety of epithelial organs. P63 was localized in the basal cells of squamous epithelium and urethral epithelium, myoepithelial cells of breast, sweat gland and salivary gland, basal cells of prostate and basal cells of skin squamous epithelium. P63 is a marker of basal cell carcinoma, squamous cell carcinoma and urinary tract transitional cell carcinoma. It can be used in the study of primary skin tumors, metastatic adenocarcinoma, benign and malignant breast lesions and prostate cancer.

  • 细胞定位

    Nuclear