FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
p57
反应性
Human,Mouse,Rat,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2b,Kappa
修饰-Modification
Unmodified
MW(Calculated)
50kD
MW(Observed)
57kD
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT214
免疫原
Synthesized peptide derived from human protein. AA range:200-316
特异性
The antibody can specifically recognize human p57kip2 protein.
基因名称
CDKN1C
蛋白名称
Cyclin-dependent kinase inhibitor 1C
别名
Beckwith Wiedemann syndrome;BWCR;BWS;CDKI;CDKN 1C;CDKN1C;CDN1C_HUMAN;Cyclin dependent kinase inhibitor 1C;Cyclin dependent kinase inhibitor p57;Cyclin-dependent kinase inhibitor 1C;Cyclin-dependent kinase inhibitor p57;KIP 2;KIP2;p57;p57 Kip 2;p57KIP2;WBS
Organism-1
Human
基因ID-1
1028
SwissProt-1
P49918
Organism-2
Mouse
基因ID-2
12577
SwissProt-2
P49919
背景
P57kip2 is a cell cycle inhibitor and tumor suppressor. The gene is mainly located on the mother's chromosome 11. By blocking the G1 / S phase transition in the cell cycle, we can realize the negative regulation of the cell cycle, and then prevent cell proliferation and tumor formation. In complete hydatidiform mole, there is a lack of maternal gene and p57 negative expression, while in partial hydatidiform mole, there are genes of both parents and p57 positive expression, which can be used for the study of early hydatidiform mole pregnancy.
细胞定位
Nuclear
