IRF-4/MUM1 (ABT080) mouse mAb

活动价:

¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2601864

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商品描述
  • 靶点-Target

    MUM1

  • 反应性

    Human,

  • 应用

    IHC,WB,IF,ELISA

  • 宿主物种-Host Species

    Mouse

  • 同种型-Isotype

    IgG1,Kappa

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    52kD

  • MW(Observed)

    52kD

  • 推荐稀释比

    IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein G

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    ABT080

  • 免疫原

    Synthesized peptide derived from human MUM1 AA range: 350-451

  • 特异性

    The antibody can specifically recognize human MUM1 protein.

  • 基因名称

    IRF4 MUM1

  • 蛋白名称

    MUM1

  • 别名

    Interferon regulatory factor 4;IRF 4;IRF-4;Irf4;IRF4_HUMAN;LSIRF;Lymphocyte specific interferon regulatory factor;Lymphocyte specific IRF;Lymphocyte-specific interferon regulatory factor;Multiple myeloma oncogene 1;MUM 1;MUM1;NF EM5;NF-EM5;NFEM5;PU.1 interaction partner;Sfpi1/PU.1 interaction partner;Transcriptional activator PIP

  • Organism-1

    Human

  • 基因ID-1

    3662

  • SwissProt-1

    Q15306

  • 背景

    MUM1, also known as interferon regulatory factor 4, with a molecular weight of 50 kDa, is a nuclear transcription factor necessary for the development and activation of B lymphocytes. It can regulate the proliferation and differentiation of B cells and activate T lymphocytes. It is mainly used for the study of B-cell lymphoma. It is expressed in multiple myeloma, lymphoplasmacytic lymphoma and diffuse large B-cell lymphoma. It can be used as a tissue derived immunophenotypic marker of B-cell lymphoma. At the same time, it is also expressed in RS cells in anaplastic large cell lymphoma, peripheral T-cell lymphoma and classical Hodgkin's lymphoma. It is an immunophenotypic marker of malignant lymphoma, only limited to lymphocytes and melanocytes.

  • 细胞定位

    Nuclear