FGF-2 Polyclonal Antibody
¥680.00
MutS Protein Homolog 6(MSH6) (ABT-MSH6) mouse mAb
活动价：
¥880.00
市场价：¥1280.00
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产品规格：
- 50μL
货号：
FAB2601863
- 产品信息
商品描述
靶点-Target
MSH6
反应性
Human,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
153kD
MW(Observed)
180kD
推荐稀释比
IHC 1:100-500;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT-MSH6
免疫原
Synthesized peptide derived from human MutS Protein Homolog 6(MSH6) AA range: 900-1000
特异性
The antibody can specifically recognize human MSH6 protein. In western blotting of HEK293 cell lysate, the antibody can label a 180 kDa band corresponding to MSH6, while there is no band detected in MSH6 knock out HEK293 cell lysate.
基因名称
MSH6 GTBP
蛋白名称
DNA mismatch repair protein Msh6 (hMSH6) (G/T mismatch-binding protein) (GTBP) (GTMBP) (MutS-alpha 160 kDa subunit) (p160)
别名
DNA mismatch repair protein Msh6;G/T mismatch binding protein;G/T mismatch-binding protein;GTBP;GTMBP;hMSH6;HNPCC 5;HNPCC5;HSAP;MSH 6;MSH6;MSH6_HUMAN;mutS;E. coli;homolog 6;MutS alpha 160 kDa subunit;MutS homolog 6;E. coli;mutS homolog 6;MutS-alpha 160 kDa subunit;p160;Sperm associated protein
Organism-1
Human
基因ID-1
2956
SwissProt-1
P52701
背景
MSH6 is an important gene in the human mismatch repair gene family, which is located at position 16 of the p arm of chromosome 2. Human mismatch repair genes play an important role in maintaining the integrity and stability of genetic information and avoiding genetic mutation. The deletion of this gene after mutation will make the cell mismatch repair function defective, lead to microsatellite instability (MSI), and make the tumor susceptible. Clinically, it is often used in the screening of Lynch syndrome together with mismatch repair proteins MLH1, MSH2 and PMS2.
细胞定位
Nuclear
