FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
HER2
反应性
Human,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2a,Kappa
修饰-Modification
Unmodified
MW(Calculated)
137kD
MW(Observed)
180kD
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT077
免疫原
Synthesized peptide derived from human Her-2 AA range: 300-400
特异性
The antibody can specifically recognize human Her-2 protein.
基因名称
ERBB2 HER2 MLN19 NEU NGL
蛋白名称
Her-2
别名
Verb b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog;C erb B2/neu protein;CD340;CD340 antigen;Cerb B2/neu protein;CerbB2;Erb b2 receptor tyrosine kinase 2;ErbB-2 proto-oncogene;ERBB2;ERBB2_HUMAN;HER 2;HER 2/NEU;HER2;Herstatin;Human epidermal growth factor receptor 2;Metastatic lymph node gene 19 protein;MLN 19;MLN19;NEU;NEU proto oncogene;Neuro/glioblastoma derived oncogene homolog;Neuroblastoma/glioblastoma derived oncogene homolog;NGL;p185erbB2;Proto-oncogene c-ErbB-2;Proto-oncogene Neu;Receptor tyrosine-protein kinase erbB-2;TKR1;Tyrosine kinase type cell surface receptor HER2;Tyrosine kinase-type cell surface receptor HER2;V erb b2 avian erythroblastic leukemia viral oncogene homolog 2;neuro/glioblastoma derived oncogene homolog;V erb b2 avian erythroblastic leukemia viral oncogene homolog 2;V erb b2 avian erythroblastic leukemia viral oncoprotein 2;V erb b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog;avian;V erb b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog;Verb b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog;avian;
Organism-1
Human
基因ID-1
2064
SwissProt-1
P04626
背景
HER2 is a proto-oncogene, and its expressed c-erbB-2 is a transmembrane protein of a tyrosine kinase receptor with a molecular weight of 185 kDa. The activation of HER2 gene can directly lead to the malignant transformation of some human cells or increase the malignant potential of cells. It is reported that the amplification of HER2 gene results in some breast, gastrointestinal, ovarian and endometrial cancers. Therefore, HER2 is directly targeted as a target drug for Hessaitin and other tumors.
细胞定位
Membranous
