FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Galectin-3
反应性
Human,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2b,Kappa
修饰-Modification
Unmodified
MW(Calculated)
26kD
MW(Observed)
33kD
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT-GAL3
免疫原
Synthesized peptide derived from human Galectin 3 AA range: 150-250
特异性
The antibody can specifically recognize human Galectin 3 protein. In western blotting of Hela, A431 and MCF7 cell lysates, the antibody can label a 30 kDa band corresponding to Galectin 3, while there is no band detected in Galectin 3 knock out Hela cell lysate.
基因名称
LGALS3 MAC2
蛋白名称
Galectin 3
别名
90K;90K MAC 2 BP;Basement membrane autoantigen p105;BTBD17B;Galectin 3 binding protein;Galectin-3-binding protein;L3 antigen;Lectin galactoside binding soluble 3 binding protein;Lectin galactoside-binding soluble 3-binding protein;LG3BP_HUMAN;LGALS3BP;M2BP;Mac 2 binding protein;Mac 2 BP;Mac-2 BP;Mac-2-binding protein;Mac2 BP;MAC2BP;Serum protein 90K;TANGO10B;Transport and golgi organization 10 homolog B;Tumor associated antigen 90K;Tumor-associated antigen 90K
Organism-1
Human
基因ID-1
3958
SwissProt-1
P17931
背景
Galectin-3 is a member of the β-galactose binding lectin family with a molecular weight of 30 kDa which is a chimeric structure consisting of a β-galactoside binding protein and a laminin. The main role of Galectin-3 on the cell surface is related to the adhesion between similar cells. It is expressed in a variety of organs and tissues, including neutrophils and vascular endothelial cells, but it is obviously absent in normal hepatocytes. Galectin-3 can downregulate the expression of some cancers and breast cancer associated proteins, and promote tumor metastasis. It can be used as a reference index for the degree of tumor deterioration.
细胞定位
Cytoplasmic, Nuclear
