FGF-2 Polyclonal Antibody
¥680.00
Cellular Apoptosis Susceptibility/CSE1L (PTR1397) mouse mAb
活动价：
¥880.00
市场价：¥1280.00
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产品规格：
- 50μL
货号：
FAB2601848
- 产品信息
商品描述
靶点-Target
CAS
反应性
Human,Mouse,Rat,
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG3,Kappa
修饰-Modification
Unmodified
MW(Calculated)
110kD
MW(Observed)
110kD
推荐稀释比
WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PTR1397
免疫原
Synthesized peptide derived from human protein.AA range:1-100
特异性
This antibody detects endogenous levels of CSE1L.
基因名称
CSE1L
蛋白名称
Exportin-2
别名
CSE1L;CAS;XPO2;Exportin-2;Exp2;Cellular apoptosis susceptibility protein;Chromosome segregation 1-like protein;Importin-alpha re-exporter
Organism-1
Human
基因ID-1
1434
SwissProt-1
P55060
Organism-2
Mouse
SwissProt-2
Q9ERK4
背景
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],
