- 产品信息
商品描述
靶点-Target
Desmin
反应性
Human,Mouse,Rat,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2b,Kappa
修饰-Modification
Unmodified
MW(Calculated)
53kD
MW(Observed)
60kD
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT168
免疫原
Synthesized peptide derived from human Desmin AA range: 400-470
特异性
The antibody can specifically recognize human Desmin protein.
基因名称
DES
蛋白名称
CMD1I;CSM1;CSM2;DES;DESM_HUMAN;Desmin;FLJ12025;FLJ39719;FLJ41013;FLJ41793;Intermediate filament protein;OTTHUMP00000064865
别名
CMD1I;CSM1;CSM2;DES;DESM_HUMAN;Desmin;FLJ12025;FLJ39719;FLJ41013;FLJ41793;Intermediate filament protein;OTTHUMP00000064865
Organism-1
Human
基因ID-1
1674
SwissProt-1
P17661
Organism-2
Mouse
SwissProt-2
P31001
Organism-3
Rat
SwissProt-3
P48675
背景
Desmin is an intermediate silk protein with a molecular weight of 53 kDa, which is widely distributed in smooth muscle cells, skeletal muscle cells, cardiomyocytes and myofibroblasts. It is mainly used for the diagnosis and differential diagnosis of smooth muscle tumors and striated muscle tumors. In rhabdomyosarcoma, pleomorphic rhabdomyosarcoma was strongly positive, while embryonic / acinar rhabdomyosarcoma was low or even negative. Myofibroblastoma was positive, and the fibroproliferative small round cell tumor showed paranuclear punctate staining.
细胞定位
Cytoplasmic





