FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Podoplanin
反应性
Human,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
24kD
MW(Observed)
36kD
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT513
免疫原
Synthesized peptide derived from human Podoplanin AA range: 23-100
特异性
The antibody can specifically recognize human Podoplanin protein. In western blotting of U2O2 cell lysate, the antibody can label a 36 kDa band corresponding to Podoplanin.
基因名称
PDPN GP36 PSEC0003 PSEC0025
蛋白名称
Aggrus Glycoprotein 36 Gp36 PA2.26 antigen T1-alpha T1A
别名
Aggrus;Glycoprotein 36;Gp36;PA2.26 antigen;T1-alpha;T1A
Organism-1
Human
基因ID-1
10630
SwissProt-1
Q86YL7
Organism-2
Mouse
SwissProt-2
Q62011
Organism-3
Rat
SwissProt-3
Q64294
背景
Podoplanin, also known as D2-40 or M2A, is a 38 kDa type I transmembrane mucin with multiple O-glycosylation sites. It is highly expressed in lymphatic endothelial cells, but not in blood vessels. In addition, it is also expressed in a variety of cells, such as mesothelial cells and type I alveolar epithelial cells, follicular dendritic cells, reticular cells, ovarian and testicular germ cells. Podoplanin is a very useful marker to distinguish malignant mesothelioma and adenocarcinoma, seminoma and follicular dendritic cell sarcoma. It is also the main choice to show and quantify lymphatic and intravascular tumor infiltration.
细胞定位
Cytoplasmic
