Cytokeratin 5/6 (ABT-CK5/052) mouse mAb
活动价:
市场价:¥1280.00
- 50μL
FAB2601839
- 产品信息
商品描述
靶点-Target
Cytokeratin 5/6
反应性
Human,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2a,Kappa
修饰-Modification
Unmodified
MW(Observed)
60,62kD
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT-CK5/052
免疫原
Synthesized peptide derived from human Cytokeratin 5 and Cytokeratin 6 AA range: C terminal amino acids 500-590 of Cytokeratin 5 and N terminal amino acids 2-100 of Cytokeratin 6
特异性
The antibody can recognize both human CK5 and CK6 protein, and shows no cross reaction with other typies of cytokeratin. In western blotting of A431 cell lysate, there shows a 56 kDa band dectected by the antibody.
基因名称
KRT5 KRT6A KRT6B KRT6C
蛋白名称
Keratin; type II cytoskeletal 5 ;58 kDa cytokeratin;Cytokeratin-5;CK-5;Keratin-5;K5;Type-II keratin Kb5;type II cytoskeletal 6A;Cytokeratin-6A; CK-6A; Keratin-6A; K6A; Type-II keratin Kb6; allergen Hom s 5; type II cytoskeletal 6B;Cytokeratin-6B; CK-6B; Keratin-6B; K6B; type II cytoskeletal 6C;Cytokeratin-6C; CK-6C; Keratin-6C; K6C
别名
58 kDa cytokeratin;CK-5;CK5;Cytokeratin-5;Cytokeratin5;DDD;DDD1;EBS2;epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types;K2C5_HUMAN;K5;keratin 5;epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types;Keratin 5;Keratin;keratin complex 2, basic, gene 5;keratin, type II cytoskeletal 5;Keratin-5;Keratin5;KRT 5;Krt5;KRT5A;type II cytoskeletal 5;Type-II keratin Kb5;CK 6A;CK 6B;CK 6C;CK 6D;CK 6E;CK-6B;CK-6C;CK-6E;Cytokeratin 6a;Cytokeratin 6B;Cytokeratin 6C;Cytokeratin 6D;Cytokeratin 6E;Cytokeratin-6B;Cytokeratin-6C;Cytokeratin-6E;K2C6C_HUMAN;K6a keratin;K6b keratin;K6C;K6c keratin;K6d keratin;K6e keratin;Keratin;Keratin K6h;Keratin type II cytoskeletal 6A;Keratin type II cytoskeletal 6B;Keratin type II cytoskeletal 6C;Keratin type II cytoskeletal 6D;Keratin type II cytoskeletal 6E;Keratin-6C;KRT6A;KRT6B;KRT6C;KRT6D;KRT6E;type II cytoskeletal 6C;Type-II keratin Kb12;58 kDa Cytokeratin antibody;CK-5 antibody;CK5 antibody;Cytokeratin-5 antibody;Cytokeratin5 antibody;DDD antibody;DDD1 antibody;EBS2 antibody;epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types antibody;K2C5_HUMAN antibody;K5 antibody;keratin 5;epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types;antibody;Keratin 5 antibody;Keratin antibody;keratin complex 2, basic, gene 5 antibody;keratin, type II cytoskeletal 5 antibody;Keratin-5 antibody;Keratin5 antibody;KRT 5 antibody;Krt5 antibody;KRT5A antibody;type II cytoskeletal 5 antibody;Type-II keratin Kb5 antibody
Organism-1
Human
基因ID-1
3852
SwissProt-1
P13647;P02538;P04259;P48668
背景
Cytokeratin 5/6 are high molecular weight keratins, which are normally expressed in squamous epithelium, basal cells of ductal epithelium, mesothelial cells, myoepithelium and basal cells of prostate, but not in glandular epithelium. Most adenocarcinoma are negative, and some adenocarcinoma can be weakly positive. The antibody is mainly used for the differential diagnosis of mesothelioma and adenocarcinoma, as well as the study of benign and malignant tumors of epithelial origin.
细胞定位
Cytoplasmic, Membranous





