FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Cytokeratin 19
反应性
Human,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2b,Kappa
修饰-Modification
Unmodified
MW(Calculated)
40kD
MW(Observed)
44kD
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT050
免疫原
Synthesized peptide derived from human CK19 AA range: 300-400
特异性
The antibody can specifically recognize human CK19 protein, and shows no cross reaction with CK1, 5, 6, 7, 8, 10, 13, 14, 15, 17, 18, 20.
基因名称
KRT19
蛋白名称
CK19
别名
40 kDa keRatin intermediate filament;CK 19;CK-19;CK19;Cytokeratin 19;CytokeRatin-19;K19;K1C19_HUMAN;K1CS;KeRatin 19;KeRatin type I 40 kD;KeRatin type I 40kD;KeRatin type I cytoskeletal 19;KeRatin, type I cytoskeletal 19;KeRatin, type I, 40 kd;KeRatin-19;KRT19;MGC15366
Organism-1
Human
基因ID-1
3880
SwissProt-1
P08727
背景
CK19 is a cytokeratin with a molecular weight of 40 kDa. It is mainly expressed in monolayer epithelium and ductal epithelium, and can be detected in the basal layer of squamous epithelium and epidermis. It is a good marker of epithelial differentiation. It is mainly used for the diagnosis of adenocarcinoma. Hepatocytes do not express CK19, but bile duct epithelium does, so it can be used to distinguish hepatocellular carcinoma from intrahepatic cholangiocarcinoma and metastatic adenocarcinoma. CK19 is partially or weakly expressed in normal thyroid tissue, follicular adenoma, nodular goiter and papillary hyperplasia, but it can be diffusely and strongly expressed in thyroid papillary carcinoma.
细胞定位
Cytoplasmic, Membranous
