Cytokeratin 17 (ABT-CK17) mouse mAb
活动价:
市场价:¥1280.00
- 50μL
FAB2601832
- 产品信息
商品描述
靶点-Target
Cytokeratin 17
反应性
Human,Mouse,Rat,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
48kD
MW(Observed)
48kD
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT-CK17
免疫原
Synthesized peptide derived from human Cytokeratin 17 AA range: 300-432
特异性
The antibody can specifically recognize human CK17 protein. In western blotting of Hela and A431 cell lysates, the antibody can label a 46 kDa band corresponding to CK17.
基因名称
KRT17
蛋白名称
Keratin, type I cytoskeletal 17 (39.1) (Cytokeratin-17) (CK-17) (Keratin-17) (K17)
别名
39.1;CK 17;CK-17;CytokeRatin-17;K17;K1C17_HUMAN;KeRatin 17;keRatin 17 epitope S1;keRatin 17 epitope S2;keRatin 17 epitope S4;KeRatin 17, type I;KeRatin;KeRatin type I cytoskeletal 17;keRatin, type i cytoskeletal 17 [version 1];KeRatin-17;KRT17;PC;PC2;PCHC1;type I cytoskeletal 17
Organism-1
Human
基因ID-1
3872
SwissProt-1
Q04695
背景
CK17 is a cytokeratin with a molecular weight of 46 kDa. It mainly marks the basal cells of stratified epithelium and pseudostratified epithelium. It is also expressed in myoepithelial cells of various glands such as breast, sweat and saliva. It is mainly used for the diagnosis of lung, cervical and oral squamous cell carcinoma. In breast cancer, the positive expression of CK17 is associated with poor prognosis, high tumor grade and axillary lymph node metastasis.
细胞定位
Cytoplasmic, Membranous





