Cytokeratin 17 (ABT-CK17) mouse mAb

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¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2601832

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商品描述
  • 靶点-Target

    Cytokeratin 17

  • 反应性

    Human,Mouse,Rat,

  • 应用

    IHC,WB,IF,ELISA

  • 宿主物种-Host Species

    Mouse

  • 同种型-Isotype

    IgG1,Kappa

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    48kD

  • MW(Observed)

    48kD

  • 推荐稀释比

    IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein G

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    ABT-CK17

  • 免疫原

    Synthesized peptide derived from human Cytokeratin 17 AA range: 300-432

  • 特异性

    The antibody can specifically recognize human CK17 protein. In western blotting of Hela and A431 cell lysates, the antibody can label a 46 kDa band corresponding to CK17.

  • 基因名称

    KRT17

  • 蛋白名称

    Keratin, type I cytoskeletal 17 (39.1) (Cytokeratin-17) (CK-17) (Keratin-17) (K17)

  • 别名

    39.1;CK 17;CK-17;CytokeRatin-17;K17;K1C17_HUMAN;KeRatin 17;keRatin 17 epitope S1;keRatin 17 epitope S2;keRatin 17 epitope S4;KeRatin 17, type I;KeRatin;KeRatin type I cytoskeletal 17;keRatin, type i cytoskeletal 17 [version 1];KeRatin-17;KRT17;PC;PC2;PCHC1;type I cytoskeletal 17

  • Organism-1

    Human

  • 基因ID-1

    3872

  • SwissProt-1

    Q04695

  • 背景

    CK17 is a cytokeratin with a molecular weight of 46 kDa. It mainly marks the basal cells of stratified epithelium and pseudostratified epithelium. It is also expressed in myoepithelial cells of various glands such as breast, sweat and saliva. It is mainly used for the diagnosis of lung, cervical and oral squamous cell carcinoma. In breast cancer, the positive expression of CK17 is associated with poor prognosis, high tumor grade and axillary lymph node metastasis.

  • 细胞定位

    Cytoplasmic, Membranous