FGF-2 Polyclonal Antibody
¥680.00
CD195/CCR5 (PTR1380) recombinant mouse mAb
活动价：
¥880.00
市场价：¥1280.00
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产品规格：
- 50μL
货号：
FAB2601800
- 产品信息
商品描述
靶点-Target
CKR-5
反应性
Human
应用
Flow Cyt,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Observed)
40kD
推荐稀释比
ELISA 1:5000-100000;Flow Cyt 1-2μg/Test
组成
Phosphate-buffered solution
纯化工艺
Recombinant Expression and Affinity purified
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
Please check the information on the tube
克隆性
Monoclonal
克隆号
PTR1380
免疫原
Purified recombinant human CCR5
特异性
This recombinant monoclonal antibody can detects endogenous levels of CD195 protein.
基因名称
CCR5 CMKBR5
蛋白名称
C-C chemokine receptor type 5 (C-C CKR-5) (CC-CKR-5) (CCR-5) (CCR5) (CHEMR13) (HIV-1 fusion coreceptor) (CD antigen CD195)
别名
C-C chemokine receptor type 5;C-C CKR-5;CC-CKR-5;CCR-5;CCR5;CHEMR13;HIV-1 fusion coreceptor;CD antigen CD195;
Organism-1
Human
基因ID-1
1234
SwissProt-1
P51681
Organism-2
Mouse
基因ID-2
12774
SwissProt-2
P51682
Organism-3
Rat
基因ID-3
117029
SwissProt-3
O08556
背景
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemok
细胞定位
Cell membrane ; Multi-pass membrane protein .
