CD8 a (PTR1338) mouse mAb

活动价:

¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2601798

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商品描述
  • 靶点-Target

    CD8

  • 反应性

    Mouse,

  • 应用

    IHC,WB,IF,ELISA

  • 宿主物种-Host Species

    Mouse

  • 同种型-Isotype

    IgG2b,Kappa

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    26kD

  • MW(Observed)

    30-35kD

  • 推荐稀释比

    IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein G

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    PTR1338

  • 免疫原

    Synthesized peptide derived from human CD8 a AA range: 150-235

  • 特异性

    This antibody detects endogenous levels of mouse CD8 a protein.

  • 基因名称

    CD8A MAL

  • 蛋白名称

    CD8 a

  • 别名

    T-cell surface glycoprotein CD8 alpha chain;T-lymphocyte differentiation antigen T8/Leu-2;CD antigen CD8a;

  • Organism-1

    Human

  • 基因ID-1

    925

  • SwissProt-1

    P01732

  • Organism-2

    Mouse

  • 基因ID-2

    12525

  • SwissProt-2

    P01731

  • 背景

    The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],

  • 细胞定位

    Membranous