FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SMAD1/9
反应性
Human,Mouse,Rat,Monkey,
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2a,Kappa
修饰-Modification
Unmodified
MW(Observed)
58-60kD
推荐稀释比
WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Monoclonal
克隆号
PTR2351
免疫原
Synthesized peptide derived from human Smad1/9 AA range: 400-465
特异性
This antibody detects endogenous levels of Smad1/9 protein.
基因名称
SMAD1 SMAD9
蛋白名称
Mothers against decapentaplegic homolog 1 (MAD homolog 1/9) (Mothers against DPP homolog 1/9) (JV4-1) (Mad-related protein 1) (SMAD family member 1) (SMAD 1/9) (Smad1) (hSMAD1) (Transforming growth factor-beta-signaling protein 1) (BSP-1)
Organism-1
Human
基因ID-1
4086
SwissProt-1
Q15797;O15198
Organism-2
Mouse
基因ID-2
17125
SwissProt-2
P70340
背景
SMAD family member 1(SMAD1) Homo sapiens The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-med
