FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MED1
反应性
Human,
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
220kD
MW(Observed)
220kD
推荐稀释比
WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Monoclonal
克隆号
PTR1203
免疫原
Synthesized peptide derived from human MED1. AA range: 650-750
特异性
This antibody detects endogenous levels of MED1 protein.
基因名称
MED1 ARC205 CRSP1 CRSP200 DRIP205 DRIP230 PBP PPARBP PPARGBP RB18A TRAP220 TRIP2
蛋白名称
Mediator of RNA polymerase II transcription subunit 1 (Activator-recruited cofactor 205 kDa component) (ARC205) (Mediator complex subunit 1) (Peroxisome proliferator-activated receptor-binding protein) (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TR-interacting protein 2) (TRIP-2) (Vitamin D receptor-interacting protein complex component DRIP205) (p53 regulatory protein RB18A)
别名
Mediator of RNA polymerase II transcription subunit 1;Activator-recruited cofactor 205 kDa component;ARC205;Mediator complex subunit 1;Peroxisome proliferator-activated receptor-binding protein;PBP;PPAR-binding protein;Thyroid hormone receptor-associated protein complex 220 kDa component;Trap220;Thyroid receptor-interacting protein 2;TR-interacting protein 2;TRIP-2;Vitamin D receptor-interacting protein complex component DRIP205;
Organism-1
Human
基因ID-1
5469
SwissProt-1
Q15648
Organism-2
Mouse
基因ID-2
19014
SwissProt-2
Q925J9
背景
mediator complex subunit 1(MED1) Homo sapiens The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize. [provided by RefSeq, Jul 2008],
