- 产品信息
商品描述
靶点-Target
TBX21
反应性
Human,Mouse,
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2a,Kappa
修饰-Modification
Unmodified
MW(Calculated)
58kD
MW(Observed)
62kD
推荐稀释比
WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Monoclonal
克隆号
PTR1291
免疫原
Synthesized peptide derived from human T-bet. AA range: 100-200
特异性
This antibody detects endogenous levels of T-bet protein.
基因名称
TBX21 TBET TBLYM
蛋白名称
T-box transcription factor TBX21 (T-box protein 21) (T-cell-specific T-box transcription factor T-bet) (Transcription factor TBLYM)
别名
T-box transcription factor TBX21;T-box protein 21;T-cell-specific T-box transcription factor T-bet;Transcription factor TBLYM;
Organism-1
Human
基因ID-1
30009
SwissProt-1
Q9UL17
Organism-2
Mouse
基因ID-2
57765
SwissProt-2
Q9JKD8
背景
T-box 21(TBX21) Homo sapiens This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells. [provided by RefSeq, Jul 2008],
细胞定位
Nuclear





