FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Caspase-1
反应性
Human,Mouse,Rat,Horse,Pig,
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2a,Kappa
修饰-Modification
Unmodified
MW(Calculated)
45kD
MW(Observed)
45kD
推荐稀释比
WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Monoclonal
克隆号
PTR1290
免疫原
Synthesized peptide derived from human Caspase-1 AA range: 350-404
特异性
This antibody detects endogenous levels of Caspase-1 protein.
基因名称
CASP1 IL1BC IL1BCE
蛋白名称
Caspase-1 (CASP-1) (Interleukin-1 beta convertase) (IL-1BC) (Interleukin-1 beta-converting enzyme) (ICE) (IL-1 beta-converting enzyme) (p45) [Cleaved into: Caspase-1 subunit p20; Caspase-1 subunit p10]
Organism-1
Human
基因ID-1
834
SwissProt-1
P29466
Organism-2
Mouse
基因ID-2
12362
SwissProt-2
P29452
背景
caspase 1(CASP1) Homo sapiens This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012],
