FGF-2 Polyclonal Antibody
¥680.00
Vitamin D Receptor (PTR2542) mouse mAb
活动价：
¥880.00
市场价：¥1280.00
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产品规格：
- 50μL
货号：
FAB2601764
- 产品信息
商品描述
靶点-Target
Vitamin D Receptor
反应性
Human,
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
48kD
MW(Observed)
37kD
推荐稀释比
WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PTR2542
免疫原
Synthesized peptide derived from human Vitamin D Receptor AA range: 150-250
特异性
This antibody detects endogenous levels of Vitamin D Receptor protein.
基因名称
VDR NR1I1
蛋白名称
Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor) (Nuclear receptor subfamily 1 group I member 1)
别名
Vitamin D3 receptor;VDR;1,25-dihydroxyvitamin D3 receptor;Nuclear receptor subfamily 1 group I member 1;
Organism-1
Human
基因ID-1
7421
SwissProt-1
P11473
Organism-2
Mouse
基因ID-2
22337
SwissProt-2
P48281
Organism-3
Rat
基因ID-3
24873
SwissProt-3
P13053
背景
vitamin D (1,25- dihydroxyvitamin D3) receptor(VDR) Homo sapiens This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Feb 2011],
