FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
p300
反应性
Human,Mouse,
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
264kD
MW(Observed)
264kD
推荐稀释比
WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PTR2539
免疫原
Synthesized peptide derived from human p300 AA range: 1-100
特异性
This antibody detects endogenous levels of p300 protein.
基因名称
EP300
蛋白名称
Histone acetyltransferase p300
别名
EP300;P300;Histone acetyltransferase p300;p300 HAT;E1A-associated protein p300
Organism-1
Human
基因ID-1
2033
SwissProt-1
Q09472
Organism-2
Mouse
SwissProt-2
B2RWS6
背景
E1A binding protein p300(EP300) Homo sapiens This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008],
