FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MGMT
反应性
Human,
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2b,Kappa
修饰-Modification
Unmodified
MW(Calculated)
22kD
MW(Observed)
22kD
推荐稀释比
WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Monoclonal
克隆号
PTR2300
免疫原
Synthesized peptide derived from human MGMT AA range: 1-100
特异性
This antibody detects endogenous levels of MGMT protein.
基因名称
MGMT
蛋白名称
Methylated-DNA--protein-cysteine methyltransferase (6-O-methylguanine-DNA methyltransferase) (MGMT) (O-6-methylguanine-DNA-alkyltransferase)
Organism-1
Human
基因ID-1
4255
SwissProt-1
P16455
Organism-2
Mouse
基因ID-2
17314
SwissProt-2
P26187
背景
O-6-methylguanine-DNA methyltransferase(MGMT) Homo sapiens Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma. [provided by RefSeq, Sep 2015],
细胞定位
Nuclear
