CD3 (ABT295) mouse mAb

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¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2601752

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商品描述
  • 靶点-Target

    CD3E

  • 反应性

    Human,

  • 应用

    IHC,WB,IF,ELISA

  • 宿主物种-Host Species

    Mouse

  • 同种型-Isotype

    IgG2a,Kappa

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    23kD

  • MW(Observed)

    23kD

  • 推荐稀释比

    IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein G

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    ABT295

  • 免疫原

    Synthesized peptide derived from human CD3, CD3E AA range: 1-100

  • 特异性

    The antibody can specifically recognize human CD3e protein, and shows no reaction with CD3d or CD3g. In western blotting of Jurkat cell lysate, the antibody can label a 23 kDa band corresponding to CD3e.

  • 基因名称

    CD3E T3E

  • 蛋白名称

    CD3, CD3E

  • 别名

    4930549J05Rik;A430104F18Rik;AW552088;Cd247;CD247 antigen;CD247 antigen, zeta subunit;CD247 molecule;CD3;CD3 antigen, delta subunit;CD3 delta;CD3 epsilon;CD3 eta;CD3 gamma;CD3 molecule delta polypeptide;CD3 molecule, epsilon polypeptide;CD3 molecule, gamma polypeptide;CD3 zeta;CD3-DELTA;CD3d;CD3D antigen delta polypeptide;CD3d antigen, delta polypeptide;TiT3 complex;CD3d molecule delta;CD3d molecule delta CD3 TCR complex;CD3d molecule, delta;CD3-TCR complex;CD3D_HUMAN;CD3E;CD3e antigen;CD3E antigen epsilon polypeptide;CD3e antigen, epsilon polypeptide;TiT3 complex;CD3e molecule epsilon;CD3e molecule epsilon CD3 TCR complex;CD3e molecule, epsilon;CD3-TCR complex;CD3epsilon;CD3G;CD3g antigen;CD3G antigen gamma polypeptide;CD3g antigen, gamma polypeptide;TiT3 complex;CD3g molecule gamma;CD3g molecule gamma CD3 TCR complex;CD3g molecule, gamma;CD3-TCR complex;CD3H;CD3Q;CD3Z;CD3zeta;Ctg3;FLJ17620;FLJ17664;FLJ18683;FLJ79544;FLJ94613;IMD19;Leu-4;MGC138597;OKT3, delta chain;OTTHUMP00000032544;T cell receptor;T cell receptor T3 delta chain;T cell receptor T3 gamma chain;T cell receptor T3 zeta chain;T cell receptor zeta chain;T cell surface antigen T3/Leu 4 epsilon chain;T cell surface glycoprotein CD3;T cell surface glycoprotein CD3 delta chain;T cell surface glycoprotein CD3 epsilon chain;T cell surface glycoprotein CD3 gamma chain;T cell surface glycoprotein CD3 zeta chain;T-cell antigen receptor complex, delta subunit of T3;T-cell antigen receptor complex, epsilon subunit of T3;T-cell antigen receptor complex, gamma subunit of T3;T-cell antigen receptor complex, zeta subunit of CD3;T-cell receptor T3 delta chain;T-cell receptor T3 gamma chain;T-cell surface antigen T3/Leu-4 epsilon chain;T-cell surface glycoprotein CD3 delta chain;T-cell surface glycoprotein CD3 epsilon chain;T-cell surface glycoprotein CD3 gamma chain;T3;T3d;T3e;T3g;T3z;TCRE;TCRk;Tcrz;TCRzeta

  • Organism-1

    Human

  • 基因ID-1

    916

  • SwissProt-1

    P07766

  • 背景

    CD3 protein contains ε、γ、δ and ζ four subunits, including extracellular, transmembrane and intracellular domains. CD3 is a T cell marker, which is not expressed by B cells. CD3 complex mediates TCR antigen recognition, leading to T cell proliferation and cytokine release. It is mainly used for the diagnosis of T-cell lymphoma, with high specificity but low sensitivity. In order to improve the accuracy of diagnosis, it is usually combined with CD45RO in clinical application.

  • 细胞定位

    Membranous