P-cadherin (PTR2204) mouse mAb

活动价:

¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2601747

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商品描述
  • 靶点-Target

    CDH3

  • 反应性

    Human,

  • 应用

    IHC,WB,IF,ELISA

  • 宿主物种-Host Species

    Mouse

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    91kD

  • MW(Observed)

    120kD

  • 推荐稀释比

    IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein G

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Monoclonal

  • 克隆号

    PTR2204

  • 免疫原

    Synthesized peptide derived from human P-cadherin. AA range: 450-550

  • 特异性

    This antibody detects endogenous levels of P-cadherin protein.

  • 基因名称

    CDH3 CDHP

  • 蛋白名称

    Cadherin-3 (Placental cadherin) (P-cadherin)

  • 别名

    Cadherin-3;Placental cadherin;P-cadherin;

  • Organism-1

    Human

  • 基因ID-1

    1001

  • SwissProt-1

    P22223

  • Organism-2

    Mouse

  • 基因ID-2

    12560

  • SwissProt-2

    P10287

  • 背景

    cadherin 3(CDH3) Homo sapiens This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). [provided by RefSeq, Nov 2015],

  • 细胞定位

    Membranous