- 产品信息
商品描述
靶点-Target
CDH3
反应性
Human,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
91kD
MW(Observed)
120kD
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Monoclonal
克隆号
PTR2204
免疫原
Synthesized peptide derived from human P-cadherin. AA range: 450-550
特异性
This antibody detects endogenous levels of P-cadherin protein.
基因名称
CDH3 CDHP
蛋白名称
Cadherin-3 (Placental cadherin) (P-cadherin)
别名
Cadherin-3;Placental cadherin;P-cadherin;
Organism-1
Human
基因ID-1
1001
SwissProt-1
P22223
Organism-2
Mouse
基因ID-2
12560
SwissProt-2
P10287
背景
cadherin 3(CDH3) Homo sapiens This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). [provided by RefSeq, Nov 2015],
细胞定位
Membranous





