Estrogen Receptor α (PTR2124) mouse mAb
活动价:
市场价:¥1280.00
- 50μL
FAB2601736
- 产品信息
商品描述
靶点-Target
ESR1
反应性
Human,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2b,Kappa
修饰-Modification
Unmodified
MW(Calculated)
66kD
MW(Observed)
67kD
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Monoclonal
克隆号
PTR2124
免疫原
Synthesized peptide derived from human Estrogen Receptor α. AA range: 450-595
特异性
This antibody detects endogenous levels of Estrogen Receptor α protein.
基因名称
ESR1 ESR NR3A1
蛋白名称
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
别名
Estrogen receptor;ER;ER-alpha;Estradiol receptor;Nuclear receptor subfamily 3 group A member 1;
Organism-1
Human
基因ID-1
2099
SwissProt-1
P03372
Organism-2
Mouse
基因ID-2
13982
SwissProt-2
P19785
Organism-3
Rat
基因ID-3
24890
SwissProt-3
P06211
背景
estrogen receptor 1(ESR1) Homo sapiens This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014],
细胞定位
Nuclear





