EGFR (PTR2121) mouse mAb

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¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2601735

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商品描述
  • 靶点-Target

    EGFR

  • 反应性

    Human,

  • 应用

    IHC,WB,IF,ELISA

  • 宿主物种-Host Species

    Mouse

  • 同种型-Isotype

    IgG2a,Kappa

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    134kD

  • MW(Observed)

    170kD

  • 推荐稀释比

    IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein G

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    PTR2121

  • 免疫原

    Synthetic Peptide of EGFR AA range: 300-400

  • 特异性

    This antibody detects endogenous levels of EGFR protein.

  • 基因名称

    EGFR

  • 蛋白名称

    Epidermal growth factor receptor

  • 别名

    EGFR;ERBB;ERBB1;HER1;Epidermal growth factor receptor;Proto-oncogene c-ErbB-1;Receptor tyrosine-protein kinase erbB-1

  • Organism-1

    Human

  • 基因ID-1

    1956

  • SwissProt-1

    P00533

  • Organism-2

    Mouse

  • 基因ID-2

    13649

  • SwissProt-2

    Q01279

  • 背景

    The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016],

  • 细胞定位

    Membranous