- 产品信息
商品描述
靶点-Target
ERK 1
反应性
Human,Mouse,Rat,
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
43kD
MW(Observed)
44kD
推荐稀释比
WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PTR1168
免疫原
Synthesized peptide derived from human ERK 1 AA range: 150-250
特异性
This antibody detects endogenous levels of ERK 1.
基因名称
MAPK3
蛋白名称
MAPK3
别名
ERK1;ERT2;ERK-1;PRKM3;P44ERK1;P44MAPK;HS44KDAP;HUMKER1A;p44-ERK1;p44-MAPK
Organism-1
Human
基因ID-1
5595
SwissProt-1
P27361
Organism-2
Mouse
SwissProt-2
Q63844
Organism-3
Rat
SwissProt-3
P21708
背景
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasmic, Nuclear





