CD105 (ABT-CD105) mouse mAb

活动价:

¥880.00

市场价:¥1280.00

一键复制产品信息
产品规格:
  • 50μL
货号:

FAB2601729

  • 产品信息
  • 注意事项
  • 实验验证
  • 产品声明
  • 引用文献
  • 相关产品
  • 文件下载
商品描述
  • 靶点-Target

    CD105(Endoglin)

  • 反应性

    Human,

  • 应用

    IHC,WB,IF,ELISA

  • 宿主物种-Host Species

    Mouse

  • 同种型-Isotype

    IgG2a,Kappa

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    70kD

  • MW(Observed)

    75kD

  • 推荐稀释比

    IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein G

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    ABT-CD105

  • 免疫原

    Synthesized peptide derived from human CD105(Endoglin) AA range: 400-500

  • 特异性

    The antibody can specifically recognize human CD105 protein.

  • 基因名称

    ENG END

  • 蛋白名称

    Endoglin (CD antigen CD105)

  • 别名

    AI528660;AI662476;CD 105;CD105;CD105 antigen;EGLN_HUMAN;END;Endoglin;Eng;FLJ41744;HHT1;ORW;ORW1;Osler Rendu Weber syndrome 1;RP11 228B15.2;S endoglin;S-endoglin;SN6

  • Organism-1

    Human

  • 基因ID-1

    2022

  • SwissProt-1

    P17813

  • 背景

    CD105 is a homodimeric cell membrane glycoprotein linked by disulfide bonds. It is a new class of cell adhesion molecules and plays an important role in regulating angiogenesis. As a receptor of TGF-beta, CD105 is highly expressed in vascular endothelial cells of tumor related neovascular endothelium. Therefore, the evaluation of tumor microvessel density by immunohistochemical staining is significantly correlated with tumor invasion and prognosis.

  • 细胞定位

    Cytoplasmic