- 产品信息
商品描述
靶点-Target
CD105(Endoglin)
反应性
Human,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2a,Kappa
修饰-Modification
Unmodified
MW(Calculated)
70kD
MW(Observed)
75kD
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT-CD105
免疫原
Synthesized peptide derived from human CD105(Endoglin) AA range: 400-500
特异性
The antibody can specifically recognize human CD105 protein.
基因名称
ENG END
蛋白名称
Endoglin (CD antigen CD105)
别名
AI528660;AI662476;CD 105;CD105;CD105 antigen;EGLN_HUMAN;END;Endoglin;Eng;FLJ41744;HHT1;ORW;ORW1;Osler Rendu Weber syndrome 1;RP11 228B15.2;S endoglin;S-endoglin;SN6
Organism-1
Human
基因ID-1
2022
SwissProt-1
P17813
背景
CD105 is a homodimeric cell membrane glycoprotein linked by disulfide bonds. It is a new class of cell adhesion molecules and plays an important role in regulating angiogenesis. As a receptor of TGF-beta, CD105 is highly expressed in vascular endothelial cells of tumor related neovascular endothelium. Therefore, the evaluation of tumor microvessel density by immunohistochemical staining is significantly correlated with tumor invasion and prognosis.
细胞定位
Cytoplasmic





