FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ERK 2
反应性
Human,Mouse,Rat,
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
41kD
MW(Observed)
42kD
推荐稀释比
WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PTR1173
免疫原
Synthesized peptide derived from human ERK 2 AA range: 150-250
特异性
This antibody detects endogenous levels of ERK 2.
基因名称
MAPK1
蛋白名称
Mitogen-activated protein kinase 1
别名
MAPK1;ERK2;PRKM1;PRKM2;Mitogen-activated protein kinase 1;MAP kinase 1;MAPK 1;ERT1;Extracellular signal-regulated kinase 2;ERK-2;MAP kinase isoform p42;p42-MAPK;Mitogen-activated protein kinase 2;MAP kinase 2;MAPK 2
Organism-1
Human
基因ID-1
5594
SwissProt-1
P28482
Organism-2
Mouse
基因ID-2
26413
SwissProt-2
P63085
基因ID-3
116590
背景
This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reporte
细胞定位
Cytoplasmic, Nuclear
