MUC1 (ABT100) mouse mAb

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¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2601724

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商品描述
  • 靶点-Target

    Mucin 1

  • 反应性

    Human,

  • 应用

    IHC,WB,IF,ELISA

  • 宿主物种-Host Species

    Mouse

  • 同种型-Isotype

    IgG1,Kappa

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    122kD

  • MW(Observed)

    122kD

  • 推荐稀释比

    IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein G

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    ABT100

  • 免疫原

    Synthesized peptide derived from human Epithelial Membrane Antigen(MUC1) AA range: 100-200

  • 特异性

    The antibody can specifically recognize human MUC1 protein. In western blotting of NIH3T3 cell lysate, there shows a 122 kDa band detected by the antibody.

  • 基因名称

    MUC1 PUM

  • 蛋白名称

    Mucin-1 (MUC-1) (Breast carcinoma-associated antigen DF3) (Carcinoma-associated mucin) (Episialin) (H23AG) (Krebs von den Lungen-6) (KL-6) (PEMT) (Peanut-reactive urinary mucin) (PUM) (Polymorphic epithelial mucin) (PEM) (Tumor-associated epithelial membrane antigen) (EMA) (Tumor-associated mucin) (CD antigen CD227) [Cleaved into: Mucin-1 subunit alpha (MUC1-NT) (MUC1-alpha); Mucin-1 subunit beta (MUC1-beta) (MUC1-CT)], CA 15-3, CA15 3, CA 15.3 , CA15-3, CA15.3

  • 别名

    ADMCKD;ADMCKD1;Breast carcinoma associated antigen DF3;Breast carcinoma-associated antigen DF3;CA 15-3;CA15 3;CA15 3 antigen;CA15-3;CA15.3;Cancer antigen 15-3;Carcinoma associated mucin;Carcinoma-associated mucin;CD 227;CD227;DF3 antigen;EMA;Episialin;Epithelial Membrane Antigen;H23 antigen;H23AG;KL 6;KL-6;KL6;Krebs von den Lungen-6;MAM 6;MAM6;MCD;MCKD;MCKD1;Medullary cystic kidney disease 1;autosomal dominant;Medullary cystic kidney disease, autosomal dominant;MUC 1;MUC-1;MUC-1/SEC;MUC-1/X;MUC1;MUC1-alpha;MUC1-beta;MUC1-CT;MUC1-NT;MUC1/ZD;MUC1_HUMAN;Mucin 1;Mucin 1 cell surface associated;Mucin 1 transmembrane;Mucin 1, cell surface associated;Mucin-1 subunit beta;Peanut reactive urinary mucin;Peanut-reactive urinary mucin;PEM;PEMT;Polymorphic epithelial mucin;PUM;Tumor associated epithelial membrane antigen;Tumor associated epithelial mucin;Tumor associated mucin;Tumor-associated epithelial membrane antigen;Tumor-associated mucin

  • Organism-1

    Human

  • 基因ID-1

    4582

  • SwissProt-1

    P15941

  • 背景

    MUC1 is a type I transmembrane protein with a molecular weight of 450 kDa. One of the characteristics of glandular epithelial tissue is the synthesis and secretion of MUC1. It plays an important role in epithelial renewal and differentiation, maintaining epithelial integrity and carcinogenesis and metastasis. Under normal conditions, it is mainly expressed in a variety of tissues and organs, epithelial cells near the lumen or glandular cavity, showing apical expression and polar distribution. It is also expressed in T cells, B cells and dendritic cells of hematopoietic system. It is mainly used to identify tumors of epithelial origin.

  • 细胞定位

    Cytoplasmic, Membranous