- 产品信息
商品描述
靶点-Target
Mucin 1
反应性
Human,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
122kD
MW(Observed)
122kD
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT100
免疫原
Synthesized peptide derived from human Epithelial Membrane Antigen(MUC1) AA range: 100-200
特异性
The antibody can specifically recognize human MUC1 protein. In western blotting of NIH3T3 cell lysate, there shows a 122 kDa band detected by the antibody.
基因名称
MUC1 PUM
蛋白名称
Mucin-1 (MUC-1) (Breast carcinoma-associated antigen DF3) (Carcinoma-associated mucin) (Episialin) (H23AG) (Krebs von den Lungen-6) (KL-6) (PEMT) (Peanut-reactive urinary mucin) (PUM) (Polymorphic epithelial mucin) (PEM) (Tumor-associated epithelial membrane antigen) (EMA) (Tumor-associated mucin) (CD antigen CD227) [Cleaved into: Mucin-1 subunit alpha (MUC1-NT) (MUC1-alpha); Mucin-1 subunit beta (MUC1-beta) (MUC1-CT)], CA 15-3, CA15 3, CA 15.3 , CA15-3, CA15.3
别名
ADMCKD;ADMCKD1;Breast carcinoma associated antigen DF3;Breast carcinoma-associated antigen DF3;CA 15-3;CA15 3;CA15 3 antigen;CA15-3;CA15.3;Cancer antigen 15-3;Carcinoma associated mucin;Carcinoma-associated mucin;CD 227;CD227;DF3 antigen;EMA;Episialin;Epithelial Membrane Antigen;H23 antigen;H23AG;KL 6;KL-6;KL6;Krebs von den Lungen-6;MAM 6;MAM6;MCD;MCKD;MCKD1;Medullary cystic kidney disease 1;autosomal dominant;Medullary cystic kidney disease, autosomal dominant;MUC 1;MUC-1;MUC-1/SEC;MUC-1/X;MUC1;MUC1-alpha;MUC1-beta;MUC1-CT;MUC1-NT;MUC1/ZD;MUC1_HUMAN;Mucin 1;Mucin 1 cell surface associated;Mucin 1 transmembrane;Mucin 1, cell surface associated;Mucin-1 subunit beta;Peanut reactive urinary mucin;Peanut-reactive urinary mucin;PEM;PEMT;Polymorphic epithelial mucin;PUM;Tumor associated epithelial membrane antigen;Tumor associated epithelial mucin;Tumor associated mucin;Tumor-associated epithelial membrane antigen;Tumor-associated mucin
Organism-1
Human
基因ID-1
4582
SwissProt-1
P15941
背景
MUC1 is a type I transmembrane protein with a molecular weight of 450 kDa. One of the characteristics of glandular epithelial tissue is the synthesis and secretion of MUC1. It plays an important role in epithelial renewal and differentiation, maintaining epithelial integrity and carcinogenesis and metastasis. Under normal conditions, it is mainly expressed in a variety of tissues and organs, epithelial cells near the lumen or glandular cavity, showing apical expression and polar distribution. It is also expressed in T cells, B cells and dendritic cells of hematopoietic system. It is mainly used to identify tumors of epithelial origin.
细胞定位
Cytoplasmic, Membranous





