- 产品信息
商品描述
靶点-Target
CD276
反应性
Human,Mouse,Rat,
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
57kD
MW(Observed)
110kD
推荐稀释比
WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PTR1401
免疫原
AA range: 100-200
特异性
This antibody detects endogenous levels of CD276 protein.
基因名称
CD276
蛋白名称
CD276 antigen
别名
CD276;B7H3;PSEC0249;CD276 antigen;4Ig-B7-H3;B7 homolog 3;B7-H3;Costimulatory molecule;CD276
Organism-1
Human
基因ID-1
80381
SwissProt-1
Q5ZPR3
Organism-2
Mouse
基因ID-2
102657
SwissProt-2
Q8VE98
Organism-3
Rat
基因ID-3
315716
SwissProt-3
Q7TPB4
背景
The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],
细胞定位
Membrane





