FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ZAP-70
反应性
Human,Mouse,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
70kD
MW(Observed)
70kD
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT246
免疫原
Synthesized peptide derived from human ZAP-70 AA range: 550-619
特异性
The antibody can specifically recognize human ZAP-70 protein.In western blotting of Jurkat cell lysate, the antibody can label a 70 kDa band corresponding to ZAP-70.
基因名称
ZAP70 SRK
蛋白名称
70 kDa zeta associated protein;70 kDa zeta-associated protein;EC 2.7.10.2;FLJ17670;FLJ17679;Selective T cell defect;SRK;STD;Syk related tyrosine kinase;Syk-related tyrosine kinase;Truncated ZAP kinase;Tyrosine protein kinase ZAP70;Tyrosine-protein kinase ZAP-70;TZK;ZAP 70;ZAP70;ZAP70_HUMAN;Zeta chain associated protein kinase 70kD;Zeta chain associated protein kinase 70 kDa;Zeta chain associated protein kinase 70 kDa isoform 1;Zeta chain associated protein kinase 70 kDa isoform 2;Zeta chain of T cell receptor associated protein kinase 70;Zeta chain TCR associated protein kinase 70kD;Zeta chain TCR associated protein kinase 70 kDa
别名
70 kDa zeta associated protein;70 kDa zeta-associated protein;FLJ17670;FLJ17679;Selective T cell defect;SRK;STD;Syk related tyrosine kinase;Syk-related tyrosine kinase;Truncated ZAP kinase;Tyrosine protein kinase ZAP70;Tyrosine-protein kinase ZAP-70;TZK;ZAP 70;ZAP70;ZAP70_HUMAN;Zeta chain associated protein kinase 70kD;Zeta chain associated protein kinase 70 kDa;Zeta chain associated protein kinase 70 kDa isoform 1;Zeta chain associated protein kinase 70 kDa isoform 2;Zeta chain of T cell receptor associated protein kinase 70;Zeta chain TCR associated protein kinase 70kD;Zeta chain TCR associated protein kinase 70 kDa
Organism-1
Human
基因ID-1
7535
SwissProt-1
P43403
Organism-2
Mouse
SwissProt-2
P43404
背景
This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasmic, Nuclear
