Androgen Receptor (ABT101) mouse mAb
活动价:
市场价:¥1280.00
- 50μL
FAB2601716
- 产品信息
商品描述
靶点-Target
Androgen Receptor
反应性
Human,Mouse,Rat,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2b,Kappa
修饰-Modification
Unmodified
MW(Calculated)
98kD
MW(Observed)
98kD
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
ABT101
免疫原
Synthesized peptide derived from human AR AA range: 27-150
特异性
The antibody can specifically recognize human AR protein.
基因名称
AR DHTR NR3C4
蛋白名称
AR
别名
AIS;Androgen receptor;AR;AR8;DHTR;Dihydro testosterone receptor;Dihydrotestosterone receptor;DHTR;HUMARA;HYSP1;KD;NR3C4;Nuclear receptor subfamily 3 group C member 4;NR3C4;Nuclear receptor subfamily 3 group C member 4;SBMA;SMAX1;Spinal and bulbar muscular atrophy;SBMA;Spinal and bulbar muscular atrophy;Testicular Feminization;TFM;TFM
Organism-1
Human
基因ID-1
367
SwissProt-1
P10275
背景
Androgen receptor (AR) is a member of the ligand response transcription regulator superfamily, which is expressed in prostate, testis and sweat gland. Upon AR binding the receptor, it stimulates androgen responsive genes transcription. AR plays an important role in the occurrence and development of prostate cancer. The higher the degree of differentiation of prostate cancer tissue, the higher the expression of AR, and the hormone treatment effect of positive prostate cancer patients is better. AR is mainly used for the detection of prostate cancer, guiding clinical treatment, and can also be used for other cancers such as esophageal cancer and breast cancer.
细胞定位
Nuclear





