Androgen Receptor (ABT101) mouse mAb

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¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2601716

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商品描述
  • 靶点-Target

    Androgen Receptor

  • 反应性

    Human,Mouse,Rat,

  • 应用

    IHC,WB,IF,ELISA

  • 宿主物种-Host Species

    Mouse

  • 同种型-Isotype

    IgG2b,Kappa

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    98kD

  • MW(Observed)

    98kD

  • 推荐稀释比

    IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein G

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    ABT101

  • 免疫原

    Synthesized peptide derived from human AR AA range: 27-150

  • 特异性

    The antibody can specifically recognize human AR protein.

  • 基因名称

    AR DHTR NR3C4

  • 蛋白名称

    AR

  • 别名

    AIS;Androgen receptor;AR;AR8;DHTR;Dihydro testosterone receptor;Dihydrotestosterone receptor;DHTR;HUMARA;HYSP1;KD;NR3C4;Nuclear receptor subfamily 3 group C member 4;NR3C4;Nuclear receptor subfamily 3 group C member 4;SBMA;SMAX1;Spinal and bulbar muscular atrophy;SBMA;Spinal and bulbar muscular atrophy;Testicular Feminization;TFM;TFM

  • Organism-1

    Human

  • 基因ID-1

    367

  • SwissProt-1

    P10275

  • 背景

    Androgen receptor (AR) is a member of the ligand response transcription regulator superfamily, which is expressed in prostate, testis and sweat gland. Upon AR binding the receptor, it stimulates androgen responsive genes transcription. AR plays an important role in the occurrence and development of prostate cancer. The higher the degree of differentiation of prostate cancer tissue, the higher the expression of AR, and the hormone treatment effect of positive prostate cancer patients is better. AR is mainly used for the detection of prostate cancer, guiding clinical treatment, and can also be used for other cancers such as esophageal cancer and breast cancer.

  • 细胞定位

    Nuclear