FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Vinculin
反应性
Human,Mouse,Rat,
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2a,Kappa
修饰-Modification
Unmodified
MW(Calculated)
124kD
MW(Observed)
124kD
推荐稀释比
WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT2221
免疫原
Synthesized peptide derived from human Vinculin. AA range: 100-200
特异性
This antibody detects endogenous levels of Vinculin protein.
基因名称
VCL
蛋白名称
Vinculin
别名
VCL;Vinculin;Metavinculin
Organism-1
Human
基因ID-1
7414
SwissProt-1
P18206
Organism-2
Mouse
基因ID-2
22330
SwissProt-2
Q64727
Organism-3
Rat
基因ID-3
305679
SwissProt-3
P85972
背景
Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008],
细胞定位
Membranous, Cytoplasmic
