FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
LAP
反应性
Human,Mouse,Rat,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2b,Kappa
修饰-Modification
Unmodified
MW(Calculated)
48kD
MW(Observed)
44kD
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT2173
免疫原
Synthesized peptide derived from human TGF β1 AA range: 300-390
特异性
This antibody detects endogenous levels of TGF β1 protein.
基因名称
TGFB1 TGFB
蛋白名称
Transforming growth factor beta-1 (TGF-beta-1) [Cleaved into: Latency-associated peptide (LAP)]
别名
Transforming growth factor beta-1;TGF-beta-1;[Cleaved into: Latency-associated peptide;LAP;]
Organism-1
Human
基因ID-1
7040
SwissProt-1
P01137
Organism-2
Mouse
基因ID-2
21803
SwissProt-2
P04202
Organism-3
Rat
基因ID-3
59086
SwissProt-3
P17246
背景
transforming growth factor beta 1(TGFB1) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene i
细胞定位
Cytoplasmic
