- 产品信息
商品描述
靶点-Target
CDH4
反应性
Human,Mouse,Rat,
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Unmodified
MW(Calculated)
102kD
MW(Observed)
120kD
推荐稀释比
WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Monoclonal
克隆号
PT2127
免疫原
Synthesized peptide derived from human R-Cadherin. AA range: 150-250
特异性
This antibody detects endogenous levels of R-Cadherin protein.
基因名称
CDH4
蛋白名称
Cadherin-4 (Retinal cadherin) (R-CAD) (R-cadherin)
别名
Cadherin-4;Retinal cadherin;R-CAD;R-cadherin;
Organism-1
Human
基因ID-1
1002
SwissProt-1
P55283
Organism-2
Mouse
基因ID-2
12561
SwissProt-2
P39038
Organism-3
Rat
SwissProt-3
Q63149
背景
cadherin 4(CDH4) Homo sapiens This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],
细胞定位
Membranous





