FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Glutamine synthetase
反应性
Human,Mouse,Rat,
应用
WB,IF,ELISA,IHC
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
42kD
MW(Observed)
42kD
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PTR1400
免疫原
AA range: 300-400
特异性
This antibody detects endogenous levels of Gl Syn/Glutamine Synthetase protein.
基因名称
GLUL
蛋白名称
Glutamine synthetase
别名
GLUL;GLNS;Glutamine synthetase;GS;Glutamate decarboxylase;Glutamate--ammonia ligase
Organism-1
Human
基因ID-1
2752
SwissProt-1
P15104
Organism-2
Mouse
基因ID-2
14645
SwissProt-2
P15105
Organism-3
Rat
基因ID-3
24957
SwissProt-3
P09606
背景
The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],
细胞定位
Membrane, Cytoplasm
