CD27 (PT1818) mouse mAb

活动价:

¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2601699

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商品描述
  • 靶点-Target

    CD27

  • 反应性

    Human,

  • 应用

    WB,IF,ELISA

  • 宿主物种-Host Species

    Mouse

  • 同种型-Isotype

    IgG2b,Kappa

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    29kD

  • MW(Observed)

    40kD

  • 推荐稀释比

    WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein G

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Monoclonal

  • 克隆号

    PT1818

  • 免疫原

    Synthesized peptide derived from human CD27 AA range: 160-260

  • 特异性

    This antibody detects endogenous levels of CD27 protein.

  • 基因名称

    CD27 TNFRSF7

  • 蛋白名称

    CD27 antigen (CD27L receptor) (T-cell activation antigen CD27) (T14) (Tumor necrosis factor receptor superfamily member 7) (CD antigen CD27)

  • Organism-1

    Human

  • 基因ID-1

    939

  • SwissProt-1

    P26842

  • Organism-2

    Mouse

  • 基因ID-2

    21940

  • SwissProt-2

    P41272

  • 背景

    CD27 molecule(CD27) Homo sapiens The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Membranous