- 产品信息
商品描述
靶点-Target
SOD2
反应性
Human,Mouse,Rat,
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
25kD
MW(Observed)
25kD
推荐稀释比
WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PTR1396
免疫原
AA range: 1-222
特异性
This antibody detects endogenous levels of SOD2 protein.
基因名称
SOD2
蛋白名称
Superoxide dismutase [Mn] mitochondrial
别名
SOD2;Superoxide dismutase [Mn], mitochondrial
Organism-1
Human
基因ID-1
6648
SwissProt-1
P04179
Organism-2
Mouse
基因ID-2
20656
SwissProt-2
P09671
Organism-3
Rat
基因ID-3
24787
SwissProt-3
P07895
背景
This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. [provided by RefSeq, Apr 2016],
细胞定位
Mitochondrion matrix





