FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Bcl-6
反应性
Human,Mouse,
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG3,Kappa
修饰-Modification
Unmodified
MW(Calculated)
78kD
MW(Observed)
78kD
推荐稀释比
WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PTR2017
免疫原
Synthesized peptide derived from human BCL6. AA range:250-350
特异性
This antibody detects endogenous levels of Bcl-6.
基因名称
BCL6
蛋白名称
B-cell lymphoma 6 protein
别名
BCL6;BCL5;LAZ3;ZBTB27;ZNF51;B-cell lymphoma 6 protein;BCL-6;B-cell lymphoma 5 protein;BCL-5;Protein LAZ-3;Zinc finger and BTB domain-containing protein 27;Zinc finger protein 51
Organism-1
Human
基因ID-1
604
SwissProt-1
P41182
Organism-2
Mouse
基因ID-2
12053
SwissProt-2
P41183
背景
The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015],
细胞定位
Nuclear
