- 产品信息
商品描述
靶点-Target
OCLN
反应性
Human,Mouse,Rat,
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,kappa
修饰-Modification
Unmodified
MW(Calculated)
59kD
MW(Observed)
59kD
推荐稀释比
IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PTR1394
免疫原
AA range: 1-522
特异性
This antibody detects endogenous levels of OCLN protein.
基因名称
OCLN
蛋白名称
Occludin;OCN
Organism-1
Human
基因ID-1
100506658
SwissProt-1
Q16625
Organism-2
Mouse
SwissProt-2
Q61146
Organism-3
Rat
SwissProt-3
Q6P6T5
背景
This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011],
细胞定位
Membrane





