FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CREBBP
反应性
Human,
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2b,Kappa
修饰-Modification
Unmodified
MW(Calculated)
266kD
MW(Observed)
266kD
推荐稀释比
WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Monoclonal
克隆号
PT0619
免疫原
Synthesized peptide derived from human CREBBP AA range: 900-1000
特异性
This antibody detects endogenous levels of CREBBP protein.
基因名称
CREBBP CBP
蛋白名称
CREB-binding protein (EC 2.3.1.48)
Organism-1
Human
基因ID-1
1387
SwissProt-1
Q92793
Organism-2
Mouse
SwissProt-2
P45481
背景
CREB binding protein(CREBBP) Homo sapiens This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations invo
细胞定位
Cytoplasmic, Nuclear
