Estrogen Receptor β (PT0318) mouse mAb
活动价:
市场价:¥1280.00
- 50μL
FAB2601680
- 产品信息
商品描述
靶点-Target
Estrogen Receptor-β
反应性
Human,
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2b,Kappa
修饰-Modification
Unmodified
MW(Calculated)
59kD
MW(Observed)
59kD
推荐稀释比
WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT0318
免疫原
Synthesized peptide derived from human Estrogen Receptor β AA range: 400-530
特异性
This antibody detects endogenous levels of Estrogen Receptor β protein.
基因名称
ESR2 ESTRB NR3A2
蛋白名称
Estrogen Receptor β
别名
Estrogen receptor beta;ER-beta;Nuclear receptor subfamily 3 group A member 2;
Organism-1
Human
基因ID-1
2100
SwissProt-1
Q92731
背景
This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008],
细胞定位
Nuclear





