Stat1 (PTR2109) Mouse mAb

活动价:

¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2601672

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商品描述
  • 靶点-Target

    STAT1

  • 反应性

    Human,Dog,

  • 应用

    WB,IF,ELISA

  • 宿主物种-Host Species

    Mouse

  • 同种型-Isotype

    IgG2a,Kappa

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    87kD

  • MW(Observed)

    87kD

  • 推荐稀释比

    WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein G

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Monoclonal

  • 克隆号

    PTR2109

  • 免疫原

    Synthesized peptide derived from human Stat1. AA range: 650-750

  • 特异性

    This antibody detects endogenous levels of Stat1 protein.

  • 基因名称

    STAT1

  • 蛋白名称

    Signal transducer and activator of transcription 1-alpha/beta (Transcription factor ISGF-3 components p91/p84)

  • 别名

    Signal transducer and activator of transcription 1-alpha/beta;Transcription factor ISGF-3 components p91/p84;

  • Organism-1

    Human

  • 基因ID-1

    6772

  • SwissProt-1

    P42224

  • Organism-2

    Mouse

  • SwissProt-2

    P42225

  • 背景

    signal transducer and activator of transcription 1(STAT1) Homo sapiens The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008],