- 产品信息
商品描述
靶点-Target
SphK2
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
72kD
推荐稀释比
WB 1:500-2000;IHC 1:50-200
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Monoclonal
克隆号
7A5
免疫原
Synthesized peptide derived from human SPHK2
特异性
This antibody detects endogenous levels of SPHK2 at Human, Mouse,Rat
基因名称
SPHK2
蛋白名称
SPHK2
别名
Sphingosine kinase 2;SK 2;SPK 2;
Organism-1
Human
基因ID-1
56848
SwissProt-1
Q9NRA0
Organism-2
Mouse
基因ID-2
56632
SwissProt-2
Q9JIA7
细胞定位
Cytoplasm . Nucleus . Endoplasmic reticulum . Mitochondrion inner membrane . In nucleus, located in nucleosomes where it associates with core histone proteins such as histone 3 (PubMed:19729656). In brains of patients with Alzheimer's disease, may be preferentially localized in the nucleus. Cytosolic expression decrease correlates with the density of amyloid deposits (PubMed:29615132). In apoptotic cells, colocalizes with CASP1 in cell membrane where is cleaved and released from cells in an active form (PubMed:20197547). .; [Isoform 2]: Lysosome membrane .





