FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Collagen I
反应性
Human,Mouse,Rat
应用
IF,IHC
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
139kD
推荐稀释比
IF 1:50-200;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Monoclonal
克隆号
4H10
免疫原
Synthetic Peptide of Collagen I
特异性
The antibody detects endogenous Collagen I protein
基因名称
COL1A1
蛋白名称
Collagen alpha-1(I) chain (Alpha-1 type I collagen)
别名
Collagen alpha-1;I;chain;Alpha-1 type I collagen;
Organism-1
Human
基因ID-1
1277;1278
SwissProt-1
P08123;P02452
Organism-2
Mouse
SwissProt-2
P11087
Organism-3
Rat
SwissProt-3
P02454
背景
This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008],
细胞定位
Secreted, extracellular space, extracellular matrix .
