FGF-2 Polyclonal Antibody
¥680.00
Acetyl NF kB P65(K314/K315) mouse Monoclonal Antibody(2A11)
活动价：
¥880.00
市场价：¥1280.00
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产品规格：
- 50μL
货号：
FAB2601643
- 产品信息
商品描述
靶点-Target
NFkB p65
反应性
Human,Mouse,Rat
应用
IHC,IF
宿主物种-Host Species
Mouse
修饰-Modification
Acetyl
MW(Observed)
65kD
推荐稀释比
IHC 1:50-300;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Monoclonal
克隆号
2A11
免疫原
Synthetic Peptide of Acetyl NF kB P65(K314/K315)
特异性
The antibody detects endogenous Acetyl NF kB P65(K314/K315) protein
基因名称
RELA NFKB3
蛋白名称
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
别名
Transcription factor p65;Nuclear factor NF-kappa-B p65 subunit;Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3;
Organism-1
Human
基因ID-1
5970
SwissProt-1
Q04206
Organism-2
Mouse
SwissProt-2
Q04207
背景
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],
细胞定位
Nucleus . Cytoplasm . Nuclear, but also found in the cytoplasm in an inactive form complexed to an inhibitor (I-kappa-B) (PubMed:1493333). Colocalized with DDX1 in the nucleus upon TNF-alpha induction (PubMed:19058135). Colocalizes with GFI1 in the nucleus after LPS stimulation (PubMed:20547752). Translocation to the nucleus is impaired in L.monocytogenes infection (PubMed:20855622). .
