FGF-2 Polyclonal Antibody
¥680.00
HP-1α mouse Monoclonal Antibody(5E3)
活动价：
¥880.00
市场价：¥1280.00
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产品规格：
- 50μL
货号：
FAB2601640
- 产品信息
商品描述
靶点-Target
HP1α
反应性
Human,Mouse,Rat
应用
IF,WB,IHC
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
22kD
推荐稀释比
IF 1:50-200;WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Monoclonal
克隆号
5E3
免疫原
Recombinant Protein of HP-1α
特异性
The antibody detects endogenous HP-1α protein
基因名称
CBX5 HP1A
蛋白名称
Chromobox protein homolog 5 (Antigen p25) (Heterochromatin protein 1 homolog alpha) (HP1 alpha)
别名
Chromobox protein homolog 5;Antigen p25;Heterochromatin protein 1 homolog alpha;HP1 alpha;
Organism-1
Human
基因ID-1
23468
SwissProt-1
P45973
Organism-2
Mouse
SwissProt-2
Q61686
背景
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Chromosome . Chromosome, centromere . Colocalizes with HNRNPU in the nucleus (PubMed:19617346). Component of centromeric and pericentromeric heterochromatin. Associates with chromosomes during mitosis. Associates specifically with chromatin during metaphase and anaphase. .
