TTR mouse Monoclonal Antibody(1D7)

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¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2601638

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商品描述
  • 靶点-Target

    TTR

  • 反应性

    Human

  • 应用

    IF,WB,IHC

  • 宿主物种-Host Species

    Mouse

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    16kD

  • 推荐稀释比

    IF 1:50-200;WB 1:500-2000;IHC 1:50-300

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Monoclonal

  • 克隆号

    1D7

  • 免疫原

    Recombinant Protein of TTR

  • 特异性

    The antibody detects endogenous TTR protein

  • 基因名称

    TTR PALB

  • 蛋白名称

    Transthyretin (ATTR) (Prealbumin) (TBPA)

  • 别名

    Transthyretin;ATTR;Prealbumin;TBPA;

  • Organism-1

    Human

  • 基因ID-1

    7276

  • SwissProt-1

    P02766

  • Organism-2

    Mouse

  • SwissProt-2

    P07309

  • 背景

    This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. [provided by RefSeq, Jan 2009],

  • 细胞定位

    Secreted. Cytoplasm.