FGF-2 Polyclonal Antibody
¥680.00
CHOP mouse Monoclonal Antibody(2B1)
活动价：
¥880.00
市场价：¥1280.00
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产品规格：
- 50μL
货号：
FAB2601634
- 产品信息
商品描述
靶点-Target
CHOP
反应性
Human,Rat,Mouse
应用
WB,IF,IHC
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
27kD
推荐稀释比
WB 1:1000-2000;IHC 1:100-200;IF 1:200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Monoclonal
克隆号
2B1
免疫原
Synthetic Peptide of CHOP at AA range of 10-90
特异性
CHOP protein detects endogenous levels of DDIT3
基因名称
DDIT3
蛋白名称
DDIT3
别名
DDIT3
Organism-1
Human
基因ID-1
1649
SwissProt-1
P35638
Organism-2
Mouse
SwissProt-2
P35639
Organism-3
Rat
SwissProt-3
Q62857
背景
This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010],
细胞定位
Cytoplasm . Nucleus . Present in the cytoplasm under non-stressed conditions and ER stress leads to its nuclear accumulation. .
