FGF-2 Polyclonal Antibody
¥680.00
MMP2 mouse Monoclonal Antibody(1H1)
活动价：
¥880.00
市场价：¥1280.00
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产品规格：
- 50μL
货号：
FAB2601633
- 产品信息
商品描述
靶点-Target
MMP-2
反应性
Human,Rat,Mouse
应用
WB,IHC,IF
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
64，72kD
推荐稀释比
IHC 1:100-200;WB 1:500-2000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Monoclonal
克隆号
1H1
免疫原
Synthetic Peptide of MMP2 at AA range of INTERNAL
特异性
MMP2 protein detects endogenous levels of MMP2
基因名称
MMP2
蛋白名称
MMP2
别名
MMP2
Organism-1
Human
基因ID-1
4313
SwissProt-1
P08253
Organism-2
Mouse
SwissProt-2
P33434
Organism-3
Rat
SwissProt-3
P33436
背景
matrix metallopeptidase 2(MMP2) Homo sapiens This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Win
细胞定位
[Isoform 1]: Secreted, extracellular space, extracellular matrix . Membrane. Nucleus. Colocalizes with integrin alphaV/beta3 at the membrane surface in angiogenic blood vessels and melanomas. Found in mitochondria, along microfibrils, and in nuclei of cardiomyocytes.; [Isoform 2]: Cytoplasm. Mitochondrion.
